Case of Acute Necrotising Encephalopathy of Childhood secondary to Severe Acute Respiratory Syndrome Coronavirus 2 infection

Journal of Paediatrics and Child HealthEarly View Case Report Case of Acute Necrotising Encephalopathy of Childhood secondary to Severe Acute Respiratory Syndrome Coronavirus 2 infection Jonathan W Tang, Corresponding Author Jonathan W Tang [email protected] orcid.org/0000-0002-5751-2264 Department of General Medicine, Women's and Children's Hospital, North Adelaide, South Australia, Australia Correspondence: Dr Jonathan W Tang, Department of General Medicine, Women's and Children's Hospital, 72 King William Road, North Adelaide, SA 5006, Australia. Fax: +61 (08) 8161 6246; email: [email protected]Search for more papers by this authorBrett Ritchie, Brett Ritchie Department of Microbiology and Infectious Diseases, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorAjay Taranath, Ajay Taranath orcid.org/0000-0002-2910-2436 South Australia Medical Imaging, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorKrista Mos, Krista Mos orcid.org/0000-0002-0497-3163 Department of Paediatric Critical Care Medicine, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorMichaela Baulderstone, Michaela Baulderstone Department of General Medicine, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorBrian Coppin, Brian Coppin orcid.org/0000-0002-6501-6244 Department of General Medicine, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this author Jonathan W Tang, Corresponding Author Jonathan W Tang [email protected] orcid.org/0000-0002-5751-2264 Department of General Medicine, Women's and Children's Hospital, North Adelaide, South Australia, Australia Correspondence: Dr Jonathan W Tang, Department of General Medicine, Women's and Children's Hospital, 72 King William Road, North Adelaide, SA 5006, Australia. Fax: +61 (08) 8161 6246; email: [email protected]Search for more papers by this authorBrett Ritchie, Brett Ritchie Department of Microbiology and Infectious Diseases, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorAjay Taranath, Ajay Taranath orcid.org/0000-0002-2910-2436 South Australia Medical Imaging, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorKrista Mos, Krista Mos orcid.org/0000-0002-0497-3163 Department of Paediatric Critical Care Medicine, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorMichaela Baulderstone, Michaela Baulderstone Department of General Medicine, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this authorBrian Coppin, Brian Coppin orcid.org/0000-0002-6501-6244 Department of General Medicine, Women's and Children's Hospital, North Adelaide, South Australia, AustraliaSearch for more papers by this author First published: 21 October 2023 https://doi.org/10.1111/jpc.16506 Conflict of interest: None declared. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Hemachudha P, Pongpitakmetha T, Rattanawong W et al. A case of successive development of possible acute necrotizing encephalopathy after COVID-19 pneumonia. SAGE Open Med. Case Rep. 2022; 10: 2050313X221083653. 2Paterson RW, Brown RL, Benjamin L et al. The emerging spectrum of COVID-19 neurology: Clinical, radiological and laboratory findings. Brain 2020; 143: 3104–3120. 3Wong AM, Simon EM, Zimmerman RA, Wang HS, Toh CH, Ng SH. Acute necrotizing encephalopathy of childhood: Correlation of MR findings and clinical outcome. AJNR Am. J. Neuroradiol. 2006; 27: 1919–1923. 4Wang HS, Huang SC. Acute necrotizing encephalopathy of childhood. Chang Gung Med. J. 2001; 24: 1–10. 5Neilson DE, Adams MD, Orr CM et al. Infection-triggered familial or recurrent cases of acute necrotizing encephalopathy caused by mutations in a component of the nuclear pore, RANBP2. Am. J. Hum. Genet. 2009; 84: 44–51. 6Wang PY, Yang MT, Liang JS. Acute necrotizing encephalopathy caused by SARS-CoV-2 in a child. Pediatr. Neonatol. 2022; 63: 642–644. 7Bashiri FA, Al Johani S, Hamad MH et al. Acute necrotizing encephalopathy of childhood: A multicenter experience in Saudi Arabia. Front. Pediatr. 2020; 8: 526. 8Altmayer V, Ziveri J, Frère C et al. Endothelial cell biomarkers in critically ill COVID-19 patients with encephalitis. J. Neurochem. 2022; 161: 492–505. 9Pilotto A, Masciocchi S, Volonghi I et al. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encephalitis is a cytokine release syndrome: Evidences from cerebrospinal fluid analyses. Clin. Infect. Dis. 2021; 73: e3019–e3026. 10Koh JC, Murugasu A, Krishnappa J, Thomas T. Favorable outcomes with early interleukin 6 receptor blockade in severe acute necrotizing encephalopathy of childhood. Pediatr. Neurol. 2019; 98: 80–84. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation