Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons.

Bin Yan,Yan Jin,Song Mao,Yi Zhang,Dahong Yang,Mingyang Du,Yugang Yin

Current neurovascular research（2023）

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摘要

Smurf2 overexpression facilitated the ubiquitination of FOXO4 to reduce its protein level, thereby suppressing DCDC2 transcription and restricting OGD/R-induced pyroptosis of cortical neurons.

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