Dihydroorotate dehydrogenase promotes cell proliferation and suppresses cell death in esophageal squamous cell carcinoma and colorectal carcinoma.

Zhi-Zhou Shi, Xin Jin,Wen-Ting Li, Hao Tao,Sheng-Jie Song,Ze-Wen Fan,Wen Jiang,Jian-Wei Liang,Jie Bai

Translational cancer research（2023）

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摘要

Overexpression of DHODH augments cell proliferation and suppresses cell death in ESCC and CRC, and DHODH might be developed as a potential anticancer target.

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关键词

dihydroorotate dehydrogenase,esophageal squamous cell carcinoma,cell carcinoma,cell proliferation

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