Control of mitochondrial dynamics by a fusogenic lipid

Mitochondrial fusion enables co-operation between the mitochon-drial population and is critical for mitochondrial function. Phospha-tidic acid (PA) on the mitochondrial surface has a key role in mitochon-drial fusion. A recent study by Su et al. shows that the nucleoside diphosphate (NDP) kinase NME3 recognizes PA and mediates its effects on mitochondrial dynamics. local promote branes. signaling local A Cell outer sible gation NDP by chondria