The Landscape of Clinical Whole Genome Sequencing and the Emergence of Rapid Genetic Diagnosis in Critical Care

Incorporating comprehensive genetic testing such as whole genome sequencing (WGS) into the traditional diagnostic process allows clinical teams to understand a patient’s disease at its most underlying molecular basis. With rapid-WGS becoming more accessible and affordable, a typical clinic/hospital will be able to perform it efficiently and at scale, on demand for a patient. Along with improvements in sequencing platforms, innovations in computer architecture and custom hardware are the key in realizing this vision. Their combined prowess is, and will continue to be, critical in our ability to generate, transfer, analyze, curate, and infer genomic data in real time.