Comparison of immunohistochemistry and next-generation sequencing results in oncogenic PTEN missense mutations

Moonsik Kim,Jinhee Kim,An Na Seo,Ji Yun Jeong,Nora Jee-Young Park,Gun Oh Chong,Dae Gy Hong,Ji Young Park

Pathology - Research and Practice（2023）

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摘要

PTEN missense mutation, which comprises a portion of oncogenic PTEN mutation, can manifest as a diverse immunostaining pattern. Complementary testing using both immunostaining and next-generation sequencing should be conducted to accurately evaluate the PTEN status in malignancy.

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关键词

mutations,next-generation

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