Assessment and management of patients with portopulmonary hypertension undergoing liver transplantation

Journal of Liver Transplantation(2023)

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摘要
•PoPH occurs in 5-8.5% of LT candidates and has important implications for the eligibility, feasibility and outcomes of LT.•Early recognition of PoPH is key - screen all LT candidates with TTE and confirm diagnosis and assess severity with RHC.•PAH-specific pharmacological therapy can improve haemodynamics, facilitate eligibility for LT and reduce mortality.•Improvement in pulmonary haemodynamics and the discontinuation of PAH-specific pharmacotherapy is often achievable post-LT.•Further research required to define optimal risk stratification and pharmacotherapy strategies in LT candidates with PoPH.
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关键词
portopulmonary hypertension,transplantation,liver
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