Effects of a chronic exposure to gemfibrozil in Carassius auratus

M. Blonç,N. Ruiz,J.C. Balasch,M. Llorca,M. Farré, A. Tvarijonaviciute,L. Tort,M. Teles

Journal of Hazardous Materials Advances（2023）

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摘要

•Gemfibrozil bioconcentrated in goldfish liver and muscle after exposure to 15 mg/L.•Exposure to gemfibrozil caused significant decreases in plasma cortisol and glucose.•Gemfibrozil caused a significant increase in plasmatic Total Antioxidant Status.•Genes involved in antioxidant processes were upregulated by exposure to gemfibrozil.

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关键词

Lipid regulators, Fibrates, Goldfish, Teleost, Long-term exposure

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