Linking resting state metabolite concentrations in the dorsal anterior cingulate cortex to response inhibition in OCD, a combined fMRI-MRS study

Niels T. de Joode,Anders L. Thorsen,Chris Vriend,Petra J.W. Pouwels,Anton J.L.M. van Balkom,Kristen Hagen,Olga T. Ousdal,Bjarne Hansen,Gerd Kvale,Odile A. van den Heuvel

Journal of Affective Disorders Reports（2023）

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摘要

•No association found between task performance and dACC Glx levels.•dACC Glx is associated with inhibition-related activation in HC, but not in OCD.•dACC Glx correlated positively with activation in the thalamus and brain stem in HC.•Findings suggest altered inhibition processing in OCD.•Combining MRS and fMRI could aid understanding the brain correlates of inhibition.

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关键词

dorsal anterior cingulate cortex,ocd,response inhibition,state metabolite concentrations,fmri-mrs

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