Favorable impact of therapy management by an interactive eHealth system on severe adverse events in patients with hormone receptor-positive, HER2-negative locally advanced or metastatic breast cancer treated by palbociclib and endocrine therapy

Nadia Harbeck,Ronald Kates,Timo Schinköthe,Johannes Schumacher,Rachel Wuerstlein,Tom Degenhardt,Diana Lüftner, Philip Räth,Oliver Hoffmann,Ralf Lorenz,Thomas Decker,Mattea Reinisch,Thomas Göhler,Peter Staib,Oleg Gluz,Peter A Fasching,Marcus Schmidt

Cancer Treatment Reviews（2023）

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摘要

•CANKADO is an autonomous eHealth-based platform supporting therapy management.•PreCycle trial included HR+/HER2- MBC patients receiving palbociclib + ET.•Patients were randomized between interactive CANKADO-active and CANKADO-inform.•SAE-free interval was substantially extended with CANKADO-active (HR 0.67)

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