Compromised diabetic heart function is not affected by miR-378a upregulation upon hyperglycemia.

Urszula Florczyk-Soluch, Katarzyna Polak, Reece Sabo,Alicja Martyniak,Jacek Stępniewski,Józef Dulak

Pharmacological reports : PR（2023）

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摘要

Overall, data underline the role of miR-378a in maintaining basal cardiac structural integrity while pointing to miR-378a-independent hyperglycemia-driven cardiac hypertrophy and associated dysfunction.

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关键词

MicroRNA-378a, Diabetic cardiomyopathy, Streptozotocin, Human induced pluripotent stem cells

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