Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.

Rombout B E van Amstel,Jason N Kennedy,Brendon P Scicluna,Lieuwe D J Bos,Hessel Peters-Sengers,Joe M Butler,Eddie Cano-Gamez,Julian C Knight,Alexander P J Vlaar,Olaf L Cremer,Derek C Angus,Tom van der Poll,Christopher W Seymour,Lonneke A van Vught

Intensive care medicine（2023）

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摘要

Among critically ill patients with sepsis, subtype strategies using clinical, biomarker, and transcriptomic data do not identify comparable patient populations and are likely to reflect disparate clinical characteristics and underlying biology.

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关键词

Sepsis, ARDS, Phenotype, Precision medicine, Intensive care

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