CTRP3 inhibits myocardial fibrosis through the P2X7R-NLRP3 inflammasome pathway in SHR rats.

Na Liu,Zhaowei Gong,Yang Li,Yang Xu,Yutong Guo,Wenjia Chen, Xue Sun,Xinhua Yin,Wenxiu Liu

Journal of hypertension（2023）

引用 0|浏览5

暂无评分

摘要

CTRP3 expression was decreased in the myocardium of SHR rats, and exogenous CTRP3 inhibited Ang II-induced fibrosis in cardiac fibroblasts by regulating the P2X7R-NLRP3 inflammasome pathway, suggesting that CTRP3 is a potential drug for alleviating myocardial fibrosis in hypertensive conditions.

查看译文

关键词

myocardial fibrosis,r-nlrp

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要