Hepatitis B virus core protein stabilizes RANGAP1 to upregulate KDM2A and facilitate hepatocarcinogenesis.

Hong-Juan You,Li-Hong Ma,Xing Wang,Yu-Xin Wang,Huan-Yang Zhang,En-Si Bao,Yu-Jie Zhong,Xiang-Ye Liu,De-Long Kong,Kui-Yang Zheng,Fan-Yun Kong,Ren-Xian Tang

Cellular oncology (Dordrecht)（2023）

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摘要

These findings demonstrate a novel mechanism by which HBC facilitates hepatocarcinogenesis. RANGAP1 and KDM2A could act as potential molecular targets for treating HBV-associated malignancy.

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关键词

HBC, KDM2A, RANGAP1, SYVN1, Hepatocellular carcinoma

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