Donor/recipient origin of lung cancer after lung transplantation by DNA short tandem repeat analysis.

Julien De Wolf, Edouard Robin,Alexandre Vallee, Justine Cohen,Abdul Hamid,Antoine Roux,Morgan Leguen,Romane Beaurepere,Ivan Bieche,Julien Masliah-Planchon,Matthieu Glorion, Yves Allory,Edouard Sage

Frontiers in oncology（2023）

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摘要

The prevalence of lung cancer in lung transplant recipients is very low. However, the results of our study showed heterogeneity of genetic alterations, with 21% being of recipient origin. Our results highlight the importance of donor selection and medical supervision after lung transplantation.

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关键词

lung transplantation (LT), short tandem repeat (STR), desoxyribonucleic acid (DNA), polymorphism chain reaction (PCR) transplantation, lung cancer, chimerism, STR, donor

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