Saikosaponin-d regulates angiogenesis in idiopathic pulmonary fibrosis through angiopoietin/Tie-2 pathway.

Yan Wu,Jun Zhang,Xintian Wang,Yuncong Xu,Jinxu Zheng

Acta histochemica（2023）

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摘要

This study has demonstrated that SSd could down-regulate the expression of ANG-1, Ang-2 and Tie2 in the Ang/Tie2 pathway, and may reduce lung inflammation and PF in BLM-induced mice via inhibition of angiogenesis.

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关键词

Saikosaponin -d, Angiogenesis, Idiopathic pulmonary fibrosis, Ang/Tie-2 pathway

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