Probing conformational dynamics to understand kinase inhibition

ELIFE（2023）

引用 0|浏览1

暂无评分

摘要

Why do some inhibitors select the on-state in ERK2, a kinase that is involved in many signaling pathways in cells, whereas others bind to more than one conformation?

查看译文

关键词

ERK2,MAP kinase,inhibitor,allosteric regulation,NMR,hydrogen-deuterium exchange mass spectrometry,None

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要