Primary Immune Thrombocytopenia in Pregnancy: Pathology, Diagnosis, and Management.

Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by an isolated decrease in the peripheral blood platelet count without a clear cause.[1] The reported annual incidence rate of adult ITP is 2 to 10/100,000 and is higher in women of childbearing age.[2] [3] Many factors increase the difficulty of ITP diagnosis and treatment during pregnancy, such as the decreased platelet count during normal pregnancy, accelerated platelet clearance, surgical delivery, the suspension of treatment, and immunoglobulin G antiplatelet antibodies transferred to the fetus through the placenta.[4] Early identification and correct treatment are crucial to ensuring the safety of mothers and babies.