Identifying cancer subtypes based on embryonic and hematopoietic stem cell signatures in pan-cancer.

Cellular oncology (Dordrecht)(2023)

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摘要
Our findings indicate that the ESC signature is an adverse prognostic factor in cancer, while the HSC signature and ratio of HSC/ESC signatures are positive prognostic factors. The subtyping of cancer based on ESC and HSC signatures may provide insights into cancer biology and clinical implications of cancer.
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关键词
Embryonic stem cell signature,Hematopoietic stem cell signature,Multi-omics,Pan-cancer,Subtyping
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