Expression of Wnt5a and ROR2, Components of the Noncanonical Wnt-Signaling Pathway, is Associated with Tumor Differentiation in Hepatocellular Carcinoma.

Kazuki Wakizaka,Toshiya Kamiyama,Tatsuhiko Kakisaka,Tatsuya Orimo,Akihisa Nagatsu,Takeshi Aiyama,Shunsuke Shichi,Akinobu Taketomi

Annals of surgical oncology（2023）

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摘要

The combination of ROR2 and Wnt5a may be a prognostic indicator for HCC. The Wnt5a/ROR2 signal pathway may be involved in the differentiation of HCC. This pathway may be a new therapeutic target for HCC.

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关键词

Differentiation,Hepatocellular carcinoma,Immunohistochemistry,ROR2,Wnt signaling

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