An overview of current knowledge on organophosphate di-esters in environment: Analytical methods, sources, occurrence, and behavior

Organophosphate di-esters (di-OPEs) are highly related to tri-OPEs. The presence of di-OPEs in the environment has gained global concerns, as some di-OPEs are more toxic than their respective tri-OPE compounds. In this study, current knowledge on the analytical methods, sources, environmental occurrence, and behavior of diOPEs were symmetrically reviewed by compiling data published till March 2023. The determination of diOPEs in environmental samples was exclusively achieved with liquid chromatography mass spectrometry operated in negative mode. There are several sources of di-OPEs, including industrial production, biotic and abiotic degradation from tri-OPEs under environmental conditions. A total of 14 di-OPE compounds were determined in various environments, including dust, sediment, sludge, water, and atmosphere. The widespread occurrence of di-OPEs suggested that human and ecology are generally exposed to di-OPEs. Among all environmental matrixes, more data were recorded for dust, with the highest concentration of di-OPEs up to 32,300 ng g-1. Sorption behavior, phase distribution, gas-particle partitioning behavior was investigated for certain diOPEs. Suggestions on future studies in the perspective of human exposure to and environmental behavior of diOPEs were proposed.