Deubiquitinating enzyme JOSD2 affects susceptibility of NSCLC cells to anti-cancer drugs through DNA damage repair.

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences(2023)

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摘要
Deubiquitinating enzyme JOSD2 regulates the malignant progression of NSCLC by promoting DNA damage repair pathway, and depletion of JOSD2 significantly enhances the sensitivity of NSCLC cells to DNA damage agents.
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关键词
DNA damage repair,Deubiquitinating enzyme,Drug sensitivity,Non-small cell lung carcinoma
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