Limited reduction in Clostridioides difficile and Methicillin-Resistant Staphylococcus aureus with the use of an aerosolized hydrogen peroxide disinfection system in tertiary health care facilities in Alberta, Canada

•Utilization of aerosolized hydrogen peroxide disinfection system was low in units.•Operating the system took time and led to delays to inpatient admissions.•Hospital-acquired Clostridioides difficile infections did not decrease.•Hospital-acquired methicillin-resistant Staphylococcus aureus did not decrease.•Participatory Research informed benefits and challenges of system implementation.