Pyrimidine-5-carbonitrile derivatives as sprout for CQDs proveniences: Antitumor and anti-inflammatory potentiality

•Variation in heteroatoms of CQDs proveniences & CQDs nucleation.•Tetrahydropyrimidine-5-carbonitrile as CQDs sprout for 3 CQDs proveniences.•CQDs as anti-inflammatory and anticancer drugs.•Particle size was ranged in 5.9–3.0 nm.•100 μM of TM-CQDs was shown with NO inhibition of 89 %.•Anti-tumor affinity of CQDs against breast Adenocarcinoma was approved.