A novel, rapid and eco-sustainable approach for the synthesis of novel benzothiazole derivatives as potent urease inhibitors: biological assay, molecular docking, dynamic simulation, DFT and ADMET studies

•A green strategy has been applied to synthesize novel benzothiazole compounds benzothiazole.•Antiurease activity revealed a promising results compared with thiourea as the standard urease inhibitor.•Molecular modeling studies highlight the potential of benzothiazole derivatives as inhibitors of urease.