Efficient heterologous expression of formate dehydrogenase and preliminary determination of the potential for conversion of carbon dioxide to formate

Shu-Wei Yuan,Mu-Ran Fu, Yi-Meng Xian,Hong-Ling Shi, Chun-Chang,Lun-Guang Yao,Cun-Duo Tang,Chang-Po Chen

MOLECULAR CATALYSIS（2023）

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摘要

•Three novel FDHs with higher catalytic activity toward sodium bicarbonate including FmFDH, KsFDH and SsFDH were obtained.•SsFDH has greater potential in CO2 reduction.•Catalytic mechanism of reducing CO2 to formate was explained using bioinformatic and computational biochemical methods.

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关键词

Formate dehydrogenase,CO2 reduction,Formate,Bioinformatic analysis

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