Neutralisation of SARS-CoV-2 Omicron subvariants BA.2.86 and EG.5.1 by antibodies induced by earlier infection or vaccination

Ria Lassauniere,Charlotta Polacek,Sharmin Baig,Kirsten Ellegaard, Leandro Andre Escobar-Herrera,Anders Fomsgaard,Katja Spiess,Olivier Schwartz,Delphine Planas,Etienne Simon-Loriere,Uffe Vest Schneider,Raphael Niklaus Sieber,Marc Stegger,Tyra Grove Krause,Henrik Ullum,Pikka Jokelainen,Morten Rasmussen

bioRxiv (Cold Spring Harbor Laboratory)（2023）

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摘要

Highly mutated SARS-CoV-2 Omicron subvariant BA.2.86 emerged in July 2023. We investigated the neutralisation of isolated virus by antibodies induced by earlier infection or vaccination. The neutralisation titres for BA.2.86 were comparable to those for XBB.1 and EG.5.1, by antibodies induced by XBB.1.5 or BA.4/5 breakthrough infection or BA.4/5 vaccination. ### Competing Interest Statement The authors have declared no competing interest.

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关键词

antibodies,vaccination,earlier infection,sars-cov

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