A juvenile mouse model of anti-N-methyl-D-aspartate receptor encephalitis by active immunization.

Shuyu He,Chongyang Sun, Qian Zhu,Lin Li,Jianyu Huang,Ge Wu,Yi Cao,Jianxiang Liao,Yi Lu,Qiru Su, Sufang Lin,Xiaopeng Ma,Cheng Zhong

Frontiers in molecular neuroscience（2023）

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摘要

The juvenile mouse model for anti-NMDAR encephalitis is of great importance to investigate the pathological mechanism and therapeutic strategies for the disease, and could accelerate the study of autoimmune encephalitis.

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关键词

juvenile mouse model, anti-NMDAR encephalitis, cognitive deficits, epilepsy susceptibility, active immunization

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