Intervention Nonadherence in the TrACER (S1415CD) Study: A Pragmatic Randomized Trial of a Standardized Order Entry for CSF Prescribing.

Dawn L Hershman,Aasthaa Bansal,William E Barlow,Kathryn B Arnold,Kate Watabayashi,Ari Bell-Brown,Sean D Sullivan,Gary H Lyman,Scott D Ramsey

JCO oncology practice（2023）

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摘要

In this randomized pragmatic trial aimed at improving PP-CSF prescribing, there was substantial variability in site adherence to the intervention assignment. Although the ability to opt out of the intervention is a feature of pragmatic trials, planning to estimate nonadherence is critical to ensure adequate power.

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关键词

standardized order entry,pragmatic randomized trial,tracer,intervention

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