Chromatographic purification of small extracellular vesicles using an affinity column for phospholipid membranes.

Biotechnology letters(2023)

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摘要
The sEVs were effectively purified in the bind-elute mode and the ExoPUA column can be refreshed and sterilized with sodium hydroxide (NaOH), having high potential for multiple sEV purification in a scalable and industrial manner.
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关键词
Affinity peptide, Column chromatography, Exosome, Extracellular vesicles, Purification
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