Characterization of Biology-Guided Radiotherapy Accuracy as a Function of PET Tracer Uptake

B. Han, J. Schmall, G. Bal,S. Khan, Y. Voronenko, S. Xu, L. Shi, A. Mitra, A. Groll,S. Sharma, K. Ramos, L. Shao,M. Narayanan, P. Olcott, G. Kuduvalli, N. Kovalchuk, M. Surucu

International journal of radiation oncology, biology, physics（2023）

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摘要

With sufficient tracer uptake in the target, BgRT can deliver tracked dosimetry for targets with a large respiratory motion profile. Both the good BgRT candidate and borderline cases produced clinically acceptable delivered doses, even though the borderline case was flagged by the clinical system safety checks. As expected, the delivered BgRT dose distributions were suboptimal with reduced tumor over background PET contrast.

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关键词

radiotherapy accuracy,pet tracer uptake,biology-guided

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