Clinical Impact of Contouring Variability for Prostate Cancer Tumor Boost

A.Y. Zhong,A.J. Lui,S. Kuznetsova,K. Kallis,T. Hussain,C.C. Conlin, D. Do, M. Rojo Domingo,R. Manger,P. Hua,R. Karunamuni,J. Kuperman, A.M. Dale,R. Rakow-Penner,M.E. Hahn, K.L. Moore,X. Ray,T.M. Seibert

International journal of radiation oncology, biology, physics（2023）

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摘要

Variability in radiation oncologists' prostate tumor contours can lead to clinically meaningful changes to focal RT boost plans. The probability of biochemical failure for one patient case increased from 6% to a median of 11% when using conventional MRI alone. Use of RSI may mitigate this problem by increasing the accuracy and reliability of radiation oncologists' tumor contours.

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关键词

contouring variability,prostate cancer

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