Comparison of Low Dose Rate and High Dose Rate Brachytherapy Boost Techniques in Prostate Cancer: Evaluation of Toxicity

A. Skipper, D.F. Cousins,M.S. Peach, J. Sanders,B. Libby, C. McLaughlin, D. Kundu, C. Luminais,T.N. Showalter, K. Romano

International journal of radiation oncology, biology, physics（2023）

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摘要

This comparative retrospective analysis of BT boost techniques reveals the overall rate of severe GU and GI toxicity to be low with both LDR and HDR. HDR boost appears to have a slightly more favorable ratio of Grade 1 to Grade 2 GU toxicity and improved urethra/rectum dosimetry. Our analysis suggests that the dosimetric advantages of HDR may deliver small reductions in GU toxicity.

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prostate cancer,low dose rate,high dose

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