Pathway Mutations are Associated with Clinical Outcomes in Localized Pancreatic Cancer Treated with Neoadjuvant Chemoradiation Followed by Surgery

J. Wang, T. Lin,A.V. Reddy,C. Hill,S. Sehgal, T. McPhaul,J.M. Herman, J. He,L. Zheng,J.J. Meyer, A. Narang

International journal of radiation oncology, biology, physics（2023）

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摘要

For pancreatic cancer patients that undergo neoadjuvant chemoradiation followed by oncologic resection of the primary tumor, mutations in key biological pathways are associated with OS and PFS. Characterizing the importance of common pathway mutations may become increasingly valuable to help categorize less commonly mutated genes assayed by NGS.

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关键词

pancreatic cancer,neoadjuvant chemoradiation,mutations

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