Transcriptomic heterogeneity of metastatic disease timing within metastatic castrationsensitive prostate cancer.
International journal of radiation oncology, biology, physics（2023）
摘要
We have demonstrated a potential biologic difference between metastatic timing of mCSPC. Specifically, for patients with low volume disease, those with metachronous low volume disease have a more hormone dependent transcriptional profile and exhibit a better prognosis than synchronous low volume disease.
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关键词
metastatic disease timing,prostate cancer,transcriptomic heterogeneity,metastatic disease,castration-sensitive
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