Impact of Testosterone Recovery on Clinical Outcomes of Patients Treated with Salvage Radiotherapy and Androgen Suppression: A Secondary Analysis of the NRG/RTOG 0534 Sport Phase 3 Trial

A. Dal Pra, J. Lyness,A. Pollack,P.T. Tran,B.F. Koontz, M.C. Abramowitz, B.A. Mahal,A.G. Martin,J.M. Michalski, A. Balogh, H. Lukka,S.L. Faria,G. Rodrigues, M.C. Beauchemin,R.J. Lee,S.A. Seaward, S.D. Coen,A.M. Allen,S. Pugh,F.Y. Feng

International journal of radiation oncology, biology, physics（2023）

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摘要

This work represents the largest study of T kinetics in patients treated with salvage radiation and ADT. Approximately half of patients did not normalize their T levels by 2 years. Our data validate an incremental and meaningful FFP benefit of adding short-term ADT and PLNRT to PBRT independent of T recovery.

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关键词

testosterone recovery,salvage radiotherapy,androgen suppression

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