Silencing of heat shock factor 1 (HSF1) inhibits proliferation, invasion, and epithelial-mesenchymal transition in oral squamous cell carcinoma.

Luiz Arthur Barbosa da Silva, Lucas Melo da Costa,Ana Camila Pereira Massetti, Laudenice de Lucena Pereira,Ericka Janine Dantas da Silveira,Tuula Anneli Salo,Ricardo Della Coletta,Márcia Cristina da Costa Miguel

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology（2023）

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摘要

Heat shock factor 1 may exert several functions that help maintain cell stability under the stressful conditions of the tumor microenvironment. Thus, strategies targeting the regulation of this protein may in the future be a useful therapeutic tool to control the progression of oral squamous cell carcinoma.

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heat shock factor,carcinoma

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