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Genome-first Approach of the Prevalence and Cancer Phenotypes of Pathogenic or Likely Pathogenic Germline TP53 Variants.

Kelvin C. de Andrade,Natasha T. Strande,Jung Kim,Jeremy S. Haley,Jessica N. Hatton,Megan N. Frone,Payal P. Khincha,Gretchen M. Thone,Uyenlinh L. Mirshahi, Cynthia Schneider,Heena Desai,James T. Dove,Diane T. Smelser, Penn Medicine Penn Med Biobank, Arnold J. Regeneron Genetics,Arnold J. Levine,Kara N. Maxwell,Douglas R. Stewart,David J. Carey,Sharon A. Savage

HUMAN GENETICS AND GENOMICS ADVANCES（2024）

Cited 5|Views45
Key words
genome-first,TP53,Li-Fraumeni syndrome,LFS,cancer genetics,cancer risk,inherited cancer,UK Biobank,Geisinger,Penn Medicine
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