Links between brain neuroimaging and blood inflammatory markers in urological chronic pelvic pain syndrome

Katherine T. Martucci,Bianka Karshikoff,Sean C. Mackey

Physiology & behavior（2023）

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摘要

•Plasma and fMRI data were collected from chronic pelvic pain patients and controls.•Resting-state functional connectivity was used as the brain fMRI biomarker.•IL-6 correlated with posterior cingulate cortex (PCC)-hippocampus connectivity.•GM-CSF was associated (non-significant) with PCC-amygdala connectivity.•Plasma IL-6 may relate to psychological comorbidity in chronic pelvic pain.

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关键词

Cytokine,Hippocampus,Amygdala,IL-6,fMRI,Inflammation

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