Modeling critical interaction for metastasis between circulating tumor cells (CTCs) and platelets adhered to the capillary wall.

Miljan Milosevic,Vladimir Simic,Aleksandar Nikolic,Ning Shao, Chihiro Kawamura Hashimoto,Biana Godin,Fransisca Leonard,Xuewu Liu,Milos Kojic

Computer methods and programs in biomedicine（2023）

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摘要

The computational framework that is presented, with accompanying results, can be used as a powerful tool to study biomechanical conditions for CTCs arrest in interaction with platelets, giving a prognosis of disease progression.

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关键词

Finite element analysis,Fluid-solid interaction,Incompressible deformations of solid,CTC-platelet interaction,Conditions for cell arrest,Metastasis

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