Impact of pretreatment low-abundance HIV-1 drug resistance on virological failure after 1 year of antiretroviral therapy in China.

Miaomiao Li,Chang Song,Jing Hu,Aobo Dong,Ruihua Kang,Yi Feng,Hui Xing,Yuhua Ruan,Yiming Shao,Kunxue Hong,Lingjie Liao

The Journal of antimicrobial chemotherapy（2023）

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摘要

Low-abundance PDR mutations ranging from 2% to 9% of abundance can increase the risk of virological failure. Further studies are warranted to define a clinically relevant threshold of LA-DRVs and the role of NRTI LA-DRVs.

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