Nickel-Catalyzed Reductive Cross-Coupling of Allylammonium Salts with Alkyl Iodides
The Journal of organic chemistry(2023)
摘要
An unprecedented reductive cross-coupling reaction of allylammonium salts with alkyl electrophiles has been established through C-N bond cleavage. A range of allylammonium bromides smoothly participated in the nickel-catalyzed zinc-mediated allyl-alkyl cross-electrophile coupling reaction with alkyl iodides, delivering structurally diverse alkene products in moderate to good yields with high linear selectivity. Preliminary mechanistic experiments are consistent with the formation of an alkyl radical from the alkyl iodide.
更多查看译文
关键词
allylammonium salts,alkyl iodides,nickel-catalyzed,cross-coupling
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要