Changes in myocardial blood flow in a canine model of left sided breast cancer radiotherapy.

Oi-Wai Chau,Omar El-Sherif,Matthew Mouawad,Jane M Sykes,John Butler,Heather Biernaski,Robert deKemp,Jennifer Renaud,Gerald Wisenberg,Frank S Prato,Stewart Gaede

PloS one（2023）

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摘要

In this canine model of radiotherapy for left-sided breast cancer, resting MBF increases as early as 1-week and persists for up to one year except at 3-months. This pattern is similar to that of 18FDG uptake. A possible interpretation is that the increase in resting MBF is a response to myocardial inflammation.

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关键词

myocardial blood flow,radiotherapy,breast cancer,canine model

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