Regulatory T cells are associated with the tumor immune microenvironment and immunotherapy response in triple-negative breast cancer.

Pengfei Huang,Xinyue Zhou,Minying Zheng,Yongjun Yu,Gongsheng Jin,Shiwu Zhang

Frontiers in immunology（2023）

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摘要

We established a prognostic model related to Treg infiltration and this model can be used to establish a clinically relevant classification of TNBC progression. Additionally, our work revealed the underestimable potential of TK1 as a tumor biomarker and immunotherapeutic target.

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关键词

triple-negative breast cancer, regulatory T cells, tumor microenvironment, single-cell RNA-sequencing, prognostic signature

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