Specific Cellular and Humoral Response after the Third Dose of Anti-SARS-CoV-2 RNA Vaccine in Patients with Immune-Mediated Rheumatic Diseases on Immunosuppressive Therapy.

Kauzar Mohamed Mohamed, María Paula Álvarez-Hernández,Carlos Jiménez García,Kissy Guevara-Hoyer, Dalifer Freites, Cristina Martínez Prada,Inés Pérez-Sancristóbal,Benjamín Fernández Gutiérrez,Gloria Mato Chaín,Maria Rodero,Antonia Rodríguez de la Peña, Teresa Mulero, Cecilia Bravo,Esther Toledano, Esther Culebras López, Beatriz Mediero Valeros,Pedro Pérez Segura,Silvia Sánchez-Ramón, Gloria Candelas Rodríguez

Biomedicines（2023）

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摘要

Our preliminary data show that the majority of our IMRD patients develop cellular and humoral responses after the SARS-CoV-2 booster vaccination, emphasizing the relevance of vaccination in this group. However, the magnitude of specific responses was dependent on the immunosuppressive therapy administered. Specific vaccination protocols and personalized decisions about boosters are essential for these patients.

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关键词

immunosuppressive therapy,rheumatic diseases,rna,anti-sars-cov,immune-mediated

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