Relationship between Dietary Patterns with Closure Growth Plate in 12-13 Years Old Girls in Kermanshah

Background & Objective Bone linear growth during puberty depends on several factors, including nutrition. In addition, malnutrition in children and adolescents can affect both linear growth and growth plate chondrocytes. This study was conducted to determine the association between dietary patterns, bone age status, and closure growth plate in adolescent girls. Methods and Materials In this study, a validated semi-quantitative 167-items food frequency questionnaire was used to determine major dietary patterns. Major dietary patterns were also identified by the component analysis method. Furthermore, anthropometric data and information about physical activity were collected from participants. Results In the present study, 70.3% of participants had bone age less than chronological age, and the findings related to 3 main dietary patterns were identified (healthy diet, high salt and sugar diet, and western/mixed diets). Among the 3 main dietary patterns, a healthy dietary pattern showed a significant correlation with the difference between chronological age and bone age (B=-0.106). This research reveals that adherence to a healthy diet was associated with an increase in bone age (P=0.02). Conclusion The current study showed a significant association between healthy dietary patterns and the bone age of participants. Based on the results, it can be claimed that a lack of components in dietary patterns can have a negative effect on chondrocytes of growth plates. The present findings confirm that children and adolescents who followed suitable dietary patterns were less likely to be stunted. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This research was funded by Kermanshah University of Medical Sciences (grant number: 97121). ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: Ethics committee of Kermanshah University of Medical Sciences gave ethical approval(IR.KUMS.REC.1397.081) for this work I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes The data sets generated during this study are available from the corresponding author on reasonable request via email. * ANOVA : Analysis of variance ASF : Animal source foods DEXA : Dual-energy x-ray absorptiometry FFQ : Food frequency questionnaire HBVp : High biological value proteins hPDI : Healthy plant-based diet index PDI : Plant-based diet index uPDI : Unhealthy plant-based diet index PBF : Percent body fat, SLM: Soft lean mass sIGF-1 : Serum insulin-like growth factor 1 TBW : Total body water.