Mosaic BRCA1 promoter methylation contribution in hereditary breast/ovarian cancer pedigrees.

Journal of medical genetics（2023）

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摘要

The high prevalence of mosaic meth in patients with breast/ovarian cancer with affected relatives, as well as this first description of a family aggregation of mosaic meth, shows how this de novo event can contribute to hereditary breast/ovarian cancer pedigrees.

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Epigenomics, Heredity, DNA Repair, DNA Methylation

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