Case report: Cardiac intimal sarcoma in a young child
Frontiers in Pediatrics(2023)
摘要
Undifferentiated mesenchymal tumors from the intimal layer (intimal sarcomas) are rare within the ventricles and exceptional in children. A rare case of an intimal sarcoma located in the right ventricle in a young child is presented with need for urgent surgical resection due to mechanical flow obstruction. Tumor cells showed amplification of MDM2 gene and a homozygous loss of CDKN2A on 9p21. A review of the literature regarding primary cardiac malignancies and intimal sarcoma in children is provided.
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关键词
intimal sarcoma, cardiac, child, MDM2, right ventricle (RV)
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