Single-cell RNA Sequencing of Neurofibromas Reveals a Tumor Microenvironment Favorable for Neural Regeneration and Immune Suppression in a Neurofibromatosis Type 1 Porcine Model

Dalton T. Mclean,Jennifer J. Meudt, Loren D. Lopez Rivera,Dominic T. Schomberg,Derek M. Pavelec, Tyler T. Duellman,Darya G. Buehler,Patrick B. Schwartz,Melissa Graham,Laura M. Lee, Keri D. Graff,Jamie L. Reichert, Sandra S. Bon-Durant,Charles M. Konsitzke,Sean M. Ronnekleiv-Kelly,Dhanansayan Shanmuganayagam,C. Dustin Rubinstein

Frontiers in Oncology（2023）

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neurofibromatosis type 1 (NF1),single cell RNA seq,swine,tumor microenvironment (TME),neurofibroma,cancer-associated fibroblasts (CAF),immune checkpoint,neuroregeneration

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