Regenerating gene 4 promotes chemoresistance of colorectal cancer by affecting lipid droplet synthesis and assembly.
World journal of gastroenterology（2023）
摘要
may be involved in chemoresistance through lipid droplet assembly. reduces expression of de novo lipid synthesis key enzymes by inhibiting transcription and promoting ubiquitination-mediated proteasomal degradation.
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关键词
colorectal cancer,regenerating,lipid,droplet synthesis
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